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NAC
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Got Mucus?
NAC
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People with lung problems
aren't the only ones who struggle with mucus. Since we started
providing Effervescent N-Acetyl Cysteine (NAC for
short) mostly for lung patients, we have had an increasing number
of people looking for help with the mucus associated with ALS,
commonly known as Lou Gehrig's Disease. When a professional ALS
counselor first contacted us about getting NAC for ALS patients,
we started researching internet information on any studies done
specifically on ALS and NAC, and what we found out was what he
already knew.
NAC is a derivative
of the amino acid cysteine, and may be the most thoroughly tested
and documented supplement in the world. It has been used as a
mucolytic (dissolves mucus) for well over 30 years,
but being a precursor to glutathione (GSH) is possibly
just as important to people with ALS. Glutathione is a powerful
antioxidant, which as you will see in the
studies below, slows the oxidative stress that contributes
to the progression of the disease.
Using guaifenesin (
Mucinex) and dextromethorphan, is only intended for short term
(7 days) use, and has warnings not to combine with
over 30 prescription drugs. It's meant for people
with colds who need a little help getting over the congestion.
It is not meant for serious, long term use. NAC, on the other
hand, has been proven safe over decades of research for long term
use.
But is all NAC the same? No.
After hours and hours of internet
research, our founder learned about the value of NAC for lung
patients, and knew he wanted to try it, but wanted to make sure
he got top quality. Wouldn't you? Then, either by accident or
providence, he stumbled across a Stanford University study
of N-acetyl Cysteine that led to the perfect answer for
him.
It said that N-acetyl cysteine
destabilizes and degrades in the presence of air.
The longer it's exposed, the weaker it gets. All those capsules
and tablets sitting on the shelf at American health stores somewhere
have air in the bottle, just oxidizing the quality away. Worse
than that, this oxidation slowly turns it into 'di-NAC', which
actually has the "opposite immunologic effect of the
NAC!" Why does this fact go unmentioned?
The most probable reason is
that the FDA does not regulate the production and packaging
of nutriceutical products made in this country, so "neither
the content nor purity of those NAC formulations can be reliably
judged." The production methods may not include the necessary
means to prevent the oxidation either during manufacture or product
storage, since that would greatly increase the costs of production.
That's why a hundred capsules are so inexpensive.
Maybe if you have tried N-acetyl
cysteine before and didn't get the results you were
hoping for, this is why.
Our
Quest for the Best!
Our founder was convinced that
if he could find a higher quality form of N-acetyl cysteine it
would work for him, and he was right. He finally found an effervescent
N-acetyl cysteine, which was manufactured in Germany in
a very strict environment of limited exposure to air, with individual
fizzy tablets sealed in air tight foil. Drop one in a few ounces
of water, and in moments, a tasty berry dose is ready to go. This
is the perfect form for ALS patients who have trouble swallowing.
We've already done
hundreds of hours of internet research
and saved you a lot of time, learning about NAC and where to find
the best available. In those hours, we found many medical studies
specifically on ALS and NAC, a few of which you will see below.
Besides dissolving
mucus, the fringe benefit of NAC's boosting the immune system
can be very helpful if you're caring for someone with ALS, not
only for them, but for you. A minor cold of yours might not
be so minor for the patient.
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Just
A Few of the Medical Studies on NAC and ALS:
From
the National Library of Medicine and the National Institutes of Health:
(http://www.ncbi.nlm.nih.gov/pubmed/10943709)
N-acetyl-L-cysteine improves survival and preserves motor performance
in an animal model of familial amyotrophic lateral sclerosis.
Neurology Service, Massachusetts General Hospital and Harvard Medical
School, Boston, USA.
Increasing evidence implicates oxidative damage as a major mechanism in
the pathogenesis of amyotrophic lateral sclerosis (ALS). We examined the
effect of preventative treatment with N-acetyl-L-cysteine (NAC), an agent
that reduces free radical damage, in transgenic mice with a superoxide
dismutase (SODI) mutation (G93A), used as an animal model of familial
ALS. NAC was administered at 1% concentration in the drinking water from
4-5 weeks of age. The treatment caused a significantly prolonged survival
and delayed onset of motor impairment in G93A mice treated with NAC compared
to control mice. These results provide further evidence for the involvement
of free radical damage in the G93A mice, and support the possibility that
NAC, an over-the-counter antioxidant, could be explored in clinical trials
for ALS.
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http://www.ingentaconnect.com/content/bsc/jnc/2001/00000076/00000001
/art00025;jsessionid=4slko6uhg1mrv.alexandra
N-Acetyl-l-cysteine protects SHSY5Y neuroblastoma cells from oxidative
stress and cell cytotoxicity: effects on ß-amyloid secretion and
tau phosphorylation
Abstract:
Redox changes within neurones are increasingly being implicated as an
important causative agent in brain aging and neurodegenerative diseases
such as amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD)
and Alzheimer's disease (AD). Cells have developed a number of defensive
mechanisms to maintain intracellular redox homeostasis, including the
glutathione (GSH) system and antioxidant enzymes. Here we examine the
effects of N-acetyl-l-cysteine (NAC) on ß-amyloid (Aß) secretion
and tau phosphorylation in SHSY5Y neuroblastoma cells after exposure to
oxidative stress inducing/cytotoxic compounds (H2O2, UV light and toxic
Aß peptides). Aß and tau protein are hallmark molecules in
the pathology of AD while the stress factors are implicated in the aetiology
of AD. The results show that H2O2, UV light, Aß1-42 and toxic Aß25-35,
but not the inactive Aß35-25, produce a significant induction of
oxidative stress and cell cytotoxicity. The effects are reversed when
cells are pre-treated with 30mm NAC. Cells exposed to H2O2, UV light and
Aß25-35, but not Aß35-25, secrete significantly higher amounts
of Aß1-40 and Aß1-42 into the culture medium. NAC pre-treatment
increased the release of Aß1-40 compared with controls and potentiated
the release of both Aß1-40 and Aß1-42 in Aß25-35-treated
cells. Tau phosphorylation was markedly reduced by H2O2 and UV light but
increased by Aß25-35. NAC strongly lowered phospho-tau levels in
the presence or absence of stress treatment.
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http://www.internaf.org/ataxia/NAC.html
IV. AMYOTROPHIC LATERAL SCLEROSIS (N=3)
A role of free radicals in the progression of ALS recently received support
with the discovery of linkage of familial ALS (FALS) with mutations in the
gene encoding CuZn SOD (SOD1)21. Levels of SOD1 are decreased in patients
with FALS but are often norrnal in sporadic ALS. In a patient with FALS,
FRESA analysis indicated an SOD1 activity of approximately 50% of the lower
end of the normal range. The remaining FRESA profile was normal. NAC treatment
has so far been unsuccessful in altering the progressive course of this
patient's disease. In two patients with sporadic ALS, SOD1 activity was
normal, but GSHpx and glutathione reductase activities were markedly decreased.
In these patients NAC treatment may have modified the course of the disease
as one patient (duration of treatment 12 months) has remained stable with
an increase in grip strength. A second patient has only marginally progressed
during 17 months of treatment with NAC. Recently, Louwerse et al.22 reported
on a double-blind trial of NAC in 111 patients with ALS. Patients with limb
onset but not bulbar onset of ALS had a 50% decrease in the one year mortality
rate with NAC treatment. |
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For those who have trouble
swallowing pills, the effervescent tablets are great!
Just drop one in some good water (not tap or distilled) or juice and
adjust the amount of liquid to taste.
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*Individually
sealed tablets prevent moisture and air from destabilizing and
degrading the NAC; a major problem for most other over the counter
NAC products bottled in capsule or tablet form, which exposes it
to air.
*Processed under strict environmental conditions, with extremely
limited exposure to air. Without
this costly processing, many over the counter NAC supplements often
have little or no active NAC in them, despite labeling to the contrary.
No matter how cheap they are, you'd still be paying too much.
*Better And Quicker Absorption:
With conventional solid tablets or capsules, the compounds often
dissolve slowly in the stomach, which frequently delays or reduces
absorption. Effervescent tablets on the other hand dissolve quickly
and easily in a glass of water, and the active ingredients are immediately
absorbed, completely and uniformly, upon drinking.
*Gentle On Your Stomach: Capsules and tablets sit
in your stomach for varying lengths of time, and can cause stomach
lining irritation, where effervescent is already dissolved before
swallowing.
*Problems Swallowing Pills? Effervescent is the perfect solution
if you're one of the many who don't like or have trouble swallowing
pills.
*Simple To Use, Exact Dosage: Effervescent tablets are quickly
dissolved in a glass of water or fruit juice and a fizzy, tasty
drink is ready to start working. With effervescent tablets, the
dose is standardized and the liquid quantity is variable allowing
for the great berry taste to be adjusted according to individual
preferences.
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See
how others have improved with NAC ~ |
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"
this
is one product that works as advertised. Consider me a customer
for life!"
Savannah,
As a patient suffering from ALS, I am always willing to try new
products and treatments to alleviate my symptoms. Unfortunately,
I am usually disappointed and see little, if any, positive results
from these various products. However, when a number of fellow patients
with ALS (PALS) mentioned the benefits of NAC in an online forum,
I decided to do some research. As it turns out, NAC comes in many
different forms and potencies and so it all became a bit confusing.
Because I have difficulty swallowing pills, I clicked on a link
recommended by fellow PALS, which brought me to HealthieLungs.com.
After reading the useful information provided on their website and
seeing how compatible their dissolvable tablets were with my condition,
I ordered a box.
After only two days of taking their NAC tablets I noticed a remarkable
difference! The mucus and phlegm that had haunted me were gone.
No more lying in bed at night trying to clear my throat. No more
rattling in my chest. And, no more bottles of expectorant. The NAC
I get from HealthierLungs.com is high quality, not overpriced, arrives
quickly, and most importantly...I am happy to report that this is
one product that works as advertised. Consider me a customer for
life!
Tom O.
Hollywood,
FL
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"
it
has eliminated the mucus."
Hello
My husband Paul uses the product and it works great. He has ALS
and says it helps him breathe better and it has eliminated the mucus.
He has been recommending to his friends.
Thank you.
Elizabeth A.
Chandler,
AZ
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"
my
Dr. tells most of his patients to try this product and in my case
he said it was imperative
"
Hey Savannah, it's Kim and Roger again......
Since upping the dosage from 2 to 4 wafers daily ( on my Dr.'s advice
) my nose has stopped running and my chest feels less heavy and
the amount of mucus I am producing has lessened considerably . There
also have been a lot of summertime colds going around, and I have
not come down with one, so hopefully the NAC is warding off the
offending bugs. I believe my Dr. tells most of his patients to try
this product and in my case he said it was imperative that I use
it. Thanks for your great customer service.
Sincerely,
Roger H.
Towner, ND
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"...within
2 days, I was breathing much easier."
Ms Taylor - Suffice it to say that I would not be reordering
this product if it did not work. I had a terrible cold that filled
my chest with thick mucus that I simply could not cough up, no matter
how much fluid I drank or how many nebulizer treatments I gave myself.
This product must have caused my body to reabsorb the mucus, because
within 2 days, I was breathing much easier. Thanks.
Brenda R.
Bowie, MD
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"...
how fast I started to feel better...I will never be without it."
Hi Savannah:
I'm so sorry it has taken me this long to get back with you, but
I've been feeling so much better I'm afraid to talk about it. By
the way Thank You so much for all of the information about NAC it
cleared up a lot of questions I had & at this point all I can
say is I will never be without it - it's just hard to believe I've
gone all these years feeling so bad & this in a very short amount
has made feel this good.
I have had upper respiratory problems all of my life, really since
I was an infant I've battled one upper respiratory infection after
another. I have taken antibiotics literally all of my life - I can't
remember a year that I wasn't on an antibiotic for bronchitis or
sinusitis or strep throat - it was never ending. I had sinus surgery
in April & appeared to be getting better & then I got bronchitis
I saw my pulmonary Dr. & he gave me some more antibiotics &
many inhalers & a breathing machine. I thought it just a matter
of time that this would take my life.
One night I found this web site about lung diseases & bronchitis
& there was an article about NAC - everything I read sounded
like a good idea & at this point I thought what do I have to
lose, so I ordered it & it was the best thing I have ever done.
I cant begin to tell you how fast I started to feel better. I had
this horrible cough, wheezing short of breath & no energy. Within
a week I started to feel so much better & it just continued.
I was so skeptical - I had tried so many things throughout the years
to no avail but this was amazing. It has truly changed my life.
Anyone with upper respiratory problems please give NAC a try, if
you don't understand how it works Savannah is there to answer any
questions you may have.
I'm so happy I found this product it has given me a new out look
on life. I feel so much better & I attribute it to NAC.
Thanks again Savannah
Pam K.
Jackson, MI
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"...I
experienced immediate relief..."
Dear Savannah,
I must admit I was a bit skeptical at first, but your product is
everything that you claim it to be. I experienced immediate relief
and have been enjoying much improved breathing since. Please re-order
my original order for five (5) boxes of NAC."
Sincerely,
James M.
Oceanside,
CA
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Box of 40 -
$24 + postage from Germany
Minimum order 4 boxes
Go
to Order Page!
600 mg. effervescent wafers
Take 1 twice a day
PayPal account
not required
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What should you
expect? Most people
report noticeable mucus reduction in as little as 2-4 days with continuing
improvement. Measurable elevation of glutathione in your blood begins
in 1 to 2 hours. The antioxidant protection from oxidative
stress begins immediately. This is a high quality, superior product
from Germany, made with a pharmaceutical precision. Dosage and usage
information in English will be included with your order.
While drugs may offer fast
relief, it's temporary and probably harmful for long term use.
Taking Effervescent NAC daily builds and maintains improvement
naturally, as well as provides all the fringe benefits
that maximize your health potential.
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Customer
Service Guarantee
We all know what good service is, and
like our privacy policy, it's as simple as The Golden Rule.
Communication, concern, courtesy and delivery are my promise to
you. I'm the Customer Service Specialist for HealthierLungs, and
it's my goal to leave no doubt in your mind that here, it's
all about YOU! You should expect an effective, high
quality product at an affordable price with
no pumped up handling charges. And if you need help, you'll get
more than you expect.
Savannah Taylor
Customer Service Specialist
HealthierLungs.com
404-431-7332 (10 to 4 ET M-F)
savannah@healthierlungs.com (after hours and weekends)
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Privacy Policy
Our privacy policy is as
simple as the Golden Rule. We will never share, rent, lease, exchange
or sell your personal information to anyone at any time for any reason.
We analyze activity on our site, to improve the site and your use of
it. This information is used only by us. We may send you a newsletter
via email, from which you would be able to opt out for further editions.
Your transaction is secured with Paypal's world class SSL Certificate
256-bit encryption.
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Refund and Return Policy
If, for any reason, you decide
that NAC is not for you, we will gladly return the full purchase price
for all unused boxes that are returned to our US address no less than
a year from the expiration date on the box. We'll even pay the return
shipping, using First Class US Mail. We suggest saving the original
shipping box for reuse, not only for your economy, but for our environment.
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We present you with public information for your own education about your
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